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KMID : 1812020110170040381
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Journal of Neurogastroenterology and Motility
2011 Volume.17 No. 4 p.381 ~ p.386
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Physicians and Patients Measure Different Dimension on Assessment for Gatroesophageal Reflux Disease-Related Symptoms
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Abstract
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Background/Aims: Gastroesophageal reflux disease is a highly prevalent disease. Assessing treatment efficacy is critical in that clinical endpoints are properly evaluated. Clinical tools for symptoms severity assessment should be discriminative, predictive and evaluative.
Methods: In this study we compared a patient-oriented symptoms evaluation (ReQuestTM) vs a structured interview assessment initiated by a physician (sickness impact profile [SIP]). Both questionnaires were analyzed in a multidimensional space using latent factors. Five dimensions were found: 1 for the short ReQuestTM questionnaire and 4 for SIP.
Results: We included 1,522 women and 1,296 men; mean age was 36 ± 7 years, and mean body mass index was 26 ± 4. The score questionnaire assessment evaluation by physicians and patients did not correlate between them (between r = 0.03 and 0.26) except nausea and sleep disorder (r = 0.45 and 0.51) but both were sensitive enough to detect changes after treatment (P ＜ 0.05). Medical specialty of the physician showed effect on the score of both, ReQuestTM and SIP evaluation. Questionnaire variance decomposition due to specialist was only 2% (P ＜ 0.05).
Conclusions: While both evaluations are orthogonal (non-correlated), meaning patients and physicians measured diverse aspects of the same disease, they both were able to measure patient’s improvement with treatment.
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KEYWORD
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Monitoring, Physiologic, Pantoprazole, Questionnaires
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